2-[2-(dimethylamino)ethylthio]-6,6-dimethyl-5,8-dihydropyrano[4,5]thieno[1,2-c]pyrimidin-4-amine profile

ID Source	ID
PubMed CID	663480
CHEMBL ID	1499120
CHEBI ID	116490

Synonym
2-{[2-(dimethylamino)ethyl]sulfanyl}-6,6-dimethyl-5,8-dihydro-6h-pyrano[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine
STL342703
smr000044281
MLS000082587 ,
CHEBI:116490
HMS2441P24
AKOS022110551
CHEMBL1499120
Q27199376
2-[2-(dimethylamino)ethylthio]-6,6-dimethyl-5,8-dihydropyrano[4,5]thieno[1,2-c]pyrimidin-4-amine
5-[2-(dimethylamino)ethylsulfanyl]-12,12-dimethyl-11-oxa-8-thia-4,6-diazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6-tetraen-3-amine

Class	Description
organic heterobicyclic compound
organonitrogen heterocyclic compound	Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms.
organosulfur heterocyclic compound
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
Chain A, Beta-lactamase	Escherichia coli K-12	Potency	56.2341	0.0447	17.8581	100.0000	AID485294
glp-1 receptor, partial	Homo sapiens (human)	Potency	1.9953	0.0184	6.8060	14.1254	AID624417
15-lipoxygenase, partial	Homo sapiens (human)	Potency	10.0000	0.0126	10.6917	88.5700	AID887
IDH1	Homo sapiens (human)	Potency	35.4813	0.0052	10.8652	35.4813	AID686970
euchromatic histone-lysine N-methyltransferase 2	Homo sapiens (human)	Potency	39.8107	0.0355	20.9770	89.1251	AID504332
cellular tumor antigen p53 isoform a	Homo sapiens (human)	Potency	31.6228	0.3162	12.4435	31.6228	AID902
chromobox protein homolog 1	Homo sapiens (human)	Potency	100.0000	0.0060	26.1688	89.1251	AID540317
serine/threonine-protein kinase PLK1	Homo sapiens (human)	Potency	29.9349	0.1683	16.4040	67.0158	AID720504
DNA polymerase iota isoform a (long)	Homo sapiens (human)	Potency	100.0000	0.0501	27.0736	89.1251	AID588590
geminin	Homo sapiens (human)	Potency	9.1911	0.0046	11.3741	33.4983	AID624296; AID624297
muscleblind-like protein 1 isoform 1	Homo sapiens (human)	Potency	19.9526	0.0041	9.9625	28.1838	AID2675
caspase-1 isoform alpha precursor	Homo sapiens (human)	Potency	19.9526	0.0003	11.4484	31.6228	AID900
Caspase-7	Homo sapiens (human)	Potency	15.8489	3.9811	18.5856	31.6228	AID889
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
proteolysis	Caspase-7	Homo sapiens (human)
apoptotic process	Caspase-7	Homo sapiens (human)
heart development	Caspase-7	Homo sapiens (human)
response to UV	Caspase-7	Homo sapiens (human)
protein processing	Caspase-7	Homo sapiens (human)
protein catabolic process	Caspase-7	Homo sapiens (human)
defense response to bacterium	Caspase-7	Homo sapiens (human)
fibroblast apoptotic process	Caspase-7	Homo sapiens (human)
striated muscle cell differentiation	Caspase-7	Homo sapiens (human)
neuron apoptotic process	Caspase-7	Homo sapiens (human)
protein maturation	Caspase-7	Homo sapiens (human)
lymphocyte apoptotic process	Caspase-7	Homo sapiens (human)
cellular response to lipopolysaccharide	Caspase-7	Homo sapiens (human)
cellular response to staurosporine	Caspase-7	Homo sapiens (human)
execution phase of apoptosis	Caspase-7	Homo sapiens (human)
positive regulation of plasma membrane repair	Caspase-7	Homo sapiens (human)
positive regulation of neuron apoptotic process	Caspase-7	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
RNA binding	Caspase-7	Homo sapiens (human)
aspartic-type endopeptidase activity	Caspase-7	Homo sapiens (human)
cysteine-type endopeptidase activity	Caspase-7	Homo sapiens (human)
protein binding	Caspase-7	Homo sapiens (human)
peptidase activity	Caspase-7	Homo sapiens (human)
cysteine-type peptidase activity	Caspase-7	Homo sapiens (human)
cysteine-type endopeptidase activity involved in apoptotic process	Caspase-7	Homo sapiens (human)
cysteine-type endopeptidase activity involved in execution phase of apoptosis	Caspase-7	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
extracellular space	Caspase-7	Homo sapiens (human)
nucleus	Caspase-7	Homo sapiens (human)
cytoplasm	Caspase-7	Homo sapiens (human)
cytosol	Caspase-7	Homo sapiens (human)
nucleus	Caspase-7	Homo sapiens (human)
nucleoplasm	Caspase-7	Homo sapiens (human)
cytosol	Caspase-7	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Assay ID	Title	Year	Journal	Article
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588497	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588499	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID651635	Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Current protocols in cytometry, Oct, Volume: Chapter 13	Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2006	Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5	Microsphere-based protease assays and screening application for lethal factor and factor Xa.
AID588501	High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set	2010	Assay and drug development technologies, Feb, Volume: 8, Issue:1	High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
AID1745845	Primary qHTS for Inhibitors of ATXN expression
AID504810	Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
AID504812	Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign	2010	Endocrinology, Jul, Volume: 151, Issue:7	A small molecule inverse agonist for the human thyroid-stimulating hormone receptor.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	3 (60.00)	24.3611
2020's	1 (20.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Description	Relationhip Strength	Classes	Roles
pilsicainide	[no description available]	low	organic heterobicyclic compound; secondary carboxamide	anti-arrhythmia drug; sodium channel blocker
pentylenetetrazole	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound
ascaridole	[no description available]	low	organic heterobicyclic compound; organic peroxide; p-menthane monoterpenoid	antileishmanial agent; antinematodal drug; plant metabolite
1,2-benzisothiazoline-3-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound	disinfectant; drug allergen; environmental contaminant; platelet aggregation inhibitor; sensitiser; xenobiotic
4,5,6,7-tetrachlorophthalide	[no description available]	low	gamma-lactone; organic heterobicyclic compound; propan-1-ol; tetrachlorobenzene	antifungal agrochemical; melanin synthesis inhibitor
nelfinavir	[no description available]	low	aryl sulfide; benzamides; organic heterobicyclic compound; phenols; secondary alcohol; tertiary amino compound	antineoplastic agent; HIV protease inhibitor
perindoprilat	[no description available]	low	dicarboxylic acid; dipeptide; L-alanine derivative; organic heterobicyclic compound	antihypertensive agent; drug metabolite; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
u 69593	[no description available]	low	monocarboxylic acid amide; N-alkylpyrrolidine; organic heterobicyclic compound; oxaspiro compound	anti-inflammatory agent; diuretic; kappa-opioid receptor agonist
perindopril	[no description available]	low	alpha-amino acid ester; dicarboxylic acid monoester; ethyl ester; organic heterobicyclic compound	antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor
verruculotoxin	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound
2,6,7,8-tetrahydrocyclopenta[2,3]thieno[2,4-d]pyrimidin-1-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
noscapine	[no description available]	low	aromatic ether; benzylisoquinoline alkaloid; cyclic acetal; isobenzofuranone; organic heterobicyclic compound; organic heterotricyclic compound; tertiary amino compound	antineoplastic agent; antitussive; apoptosis inducer; plant metabolite
1-oxo-2-benzothiopyran-3-carboxylic acid methyl ester	[no description available]	low	organic heterobicyclic compound; organosulfur heterocyclic compound
luciduline	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound
4-[2-[(4-fluorophenyl)methylamino]-2-oxoethyl]-2-methyl-5-thieno[3,2-b]pyrrolecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-cyclohexyl-N,4-dimethyl-5-thieno[3,2-b]pyrrolecarboxamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-methyl-5-thieno[3,2-b]pyrrolecarboxylic acid [1-oxo-1-(2-phenylethylamino)propan-2-yl] ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[(5,6-dimethyl-4-oxo-3H-thieno[2,3-d]pyrimidin-2-yl)thio]-N-(4-methyl-2-thiazolyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-methyl-4-[2-oxo-2-(2-phenylethylamino)ethyl]-5-thieno[3,2-b]pyrrolecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
6,6-dimethyl-5,8-dihydropyrano[4,5]thieno[1,2-c]pyrimidin-4-amine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[(2-ethyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl)thio]-N-(2-furanylmethyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[(5,6-dimethyl-4-oxo-3-phenyl-2-thieno[2,3-d]pyrimidinyl)thio]-N-(2-furanylmethyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
6-[(2-fluorophenyl)methyl]-2,4-dimethyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-methyl-5-thieno[3,2-b]pyrrolecarboxylic acid [2-oxo-2-(thiophen-2-ylmethylamino)ethyl] ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[[5-(4-methylphenyl)-3-thiazolo[2,3-c][1,2,4]triazolyl]thio]-N-(6-methyl-2-pyridinyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
7-amino-5-(4-ethoxy-3-methoxyphenyl)-4-oxo-3,5-dihydropyrano[2,3-d]pyrimidine-6-carbonitrile	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; oxacycle
6-ethyl-6-methyl-5,8-dihydro-1H-thiopyrano[2,3]thieno[2,4-b]pyrimidine-2,4-dione	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[(7-methyl-4-oxo-3-phenyl-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-b]pyrimidin-2-yl)thio]acetic acid methyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
LSM-19776	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[[6,6-dimethyl-2-(propan-2-ylthio)-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-4-yl]thio]-N-(2-furanylmethyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
1-[(4-fluorophenyl)methyl]-3-(2-furanylmethyl)-4-imino-6,6-dimethyl-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-2-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-(4-chlorophenyl)-2-[3-(2-furanylmethyl)-4-imino-6,6-dimethyl-2-oxo-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-1-yl]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3-[[2-(3,5-dimethyl-1-pyrazolyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-yl]amino]-1-propanol	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[[2-(3,5-dimethyl-1-pyrazolyl)-6,6-dimethyl-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-4-yl]thio]-N-(2-thiazolyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[3-(2-furanylmethyl)-4-imino-6,6-dimethyl-2-oxo-5,8-dihydropyrano[2,3]thieno[2,4-b]pyrimidin-1-yl]-N-phenylacetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-(1-benzotriazolyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-(2-furanyl)-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
5-(4-chlorophenyl)-3H-thieno[2,3-d]pyrimidine-4-thione	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-(2-furanylmethyl)-3-methyl-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-methyl-5-(5-methyl-2-furanyl)-3-(1-pyrrolyl)-4-thieno[2,3-d]pyrimidinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
5-methyl-6-phenyl-3H-thieno[2,3-d]pyrimidine-4-thione	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3-ethyl-5-methyl-4-oxo-6-thieno[2,3-d]pyrimidinecarboxylic acid	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3,5-dimethyl-4-[[(5-phenyl-3-thiazolo[2,3-c][1,2,4]triazolyl)thio]methyl]isoxazole	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
5,6-dimethyl-N-(3-pyridinylmethyl)-4-thieno[2,3-d]pyrimidinamine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
3-prop-2-enyl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-[1]benzothiolo[2,3-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-sulfanylidene-1,6,7,8,9,10-hexahydropyrimido[3,4]pyrrolo[3,5-a]azepine-11-carbonitrile	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound
3-amino-2-(4-methylphenyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[(3,5-dimethyl-4-isoxazolyl)methylthio]-3-prop-2-enyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3-(4-methoxyphenyl)-6-phenyl-4-thieno[2,3-d]pyrimidinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-(2-furanylmethyl)-2-(4-oxo-6-phenyl-3-thieno[2,3-d]pyrimidinyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-(5,6-dimethyl-1-benzimidazolyl)-5-phenylthieno[2,3-d]pyrimidine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
9-(dimethylamino)-3-(4-methoxyphenyl)-4-pyrido[1,2]thieno[3,4-d]pyrimidinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[2,4-dioxo-3-(2-phenylethyl)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-1-yl]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[(3,5-dimethyl-4-isoxazolyl)methylthio]-3-prop-2-enyl-6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-b]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-(1,3-benzodioxol-5-ylmethylthio)-5-(2-furanyl)-3-prop-2-enyl-4-thieno[2,3-d]pyrimidinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
LSM-24412	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
LSM-17286	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
[5,6-dimethyl-3-(pyridin-4-ylmethyl)-2,4-dihydrothieno[2,3-d]pyrimidin-1-yl]-(2-furanyl)methanone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-(1-benzimidazolyl)-5-(4-methylphenyl)thieno[2,3-d]pyrimidine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
N-(3-hydroxypropyl)-4-[(1-oxo-2,6,7,8-tetrahydrocyclopenta[2,3]thieno[2,4-b]pyrimidin-3-yl)thio]butanamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
5,6-dimethyl-2-(prop-2-enylthio)-4-thieno[2,3-d]pyrimidinamine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
4,5-dimethyl-2-[[2-(6-methyl-4-oxo-5-phenyl-3-thieno[2,3-d]pyrimidinyl)-1-oxoethyl]amino]-3-thiophenecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[3-(2-furanylmethyl)-2,4-dioxo-6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-b]pyrimidin-1-yl]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3-cyclohexyl-2-hydrazinyl-7-(phenylmethyl)-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-b]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
1-[2-(diethylamino)ethyl]-7,7-dimethyl-2-(4-methylphenyl)-5,8-dihydropyrano[4,3-d]pyrimidine-4-thione	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; oxacycle
2-(butylamino)-3-(3-chlorophenyl)-7-methyl-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-b]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-(1,3-benzodioxol-5-yl)-2-[[3-(2-methoxyphenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]thio]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
5,6-dimethyl-N-(thiophen-2-ylmethyl)-4-thieno[2,3-d]pyrimidinamine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
2-(1,3-dimethyl-2-benzimidazolylidene)-4-[(6-ethyl-4-thieno[2,3-d]pyrimidinyl)thio]-3-oxobutanenitrile	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
3-(phenylmethyl)-2-sulfanylidene-1H-thieno[3,2-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3-methyl-6-thiophen-2-yl-4-isoxazolo[5,4-b]pyridinecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; oxacycle
N-(6-methyl-1,3-benzothiazol-2-yl)-2-[(4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)thio]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[[3-(4-methylphenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]thio]-N-(2-thiazolyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[[3-(4-methoxyphenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]thio]acetic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-(2-furanylmethyl)-2-(6,7,8,9-tetrahydro-5H-cyclohepta[2,3]thieno[2,4-d]pyrimidin-4-ylthio)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-chloro-N-(2-ethyl-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-3-yl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3-methyl-N-[(4-methylphenyl)methyl]-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-(4-methoxyanilino)-2,5-dimethyl-6-thieno[2,3-d]pyrimidinecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
2-[[(2-chlorophenyl)thio]methyl]-5-methyl-4-oxo-3H-thieno[2,3-d]pyrimidine-6-carboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
5-(2-chlorophenyl)-2-(2-pyridinylmethyl)-3H-thieno[2,3-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[[[4-cyclohexyl-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]methyl]-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
5,6-dimethyl-N-[2-methyl-2-(4-morpholinyl)propyl]-4-thieno[2,3-d]pyrimidinamine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
2-[[[2-[(5-methoxycarbonyl-2-furanyl)methoxy]-2-oxoethyl]thio]methyl]-5-methyl-4-oxo-3H-thieno[2,3-d]pyrimidine-6-carboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
5-[[(5,6-dimethyl-4-thieno[2,3-d]pyrimidinyl)thio]methyl]-2-furancarboxylic acid methyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
N4-isopropyl-7-methylthieno[3,2-d]pyrimidin-4-amine	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-amino-7,8,9,10-tetrahydro-6H-pyrimido[3,4]pyrrolo[3,5-a]azepine-11-carbonitrile	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound
7-ethyl-7-methyl-2-sulfanylidene-6,9-dihydro-1H-pyrano[2,3]thieno[2,4-b]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-[[2-(dimethylamino)-2-thiophen-2-ylethyl]amino]-5-methyl-6-thieno[2,3-d]pyrimidinecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
2-[[(1-ethyl-2-benzimidazolyl)thio]methyl]-5-methyl-4-oxo-3H-thieno[2,3-d]pyrimidine-6-carboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
apramycin	[no description available]	low	2-deoxystreptamine derivative; aminoglycoside; organic heterobicyclic compound	antibacterial drug; antimicrobial agent
LSM-5894	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound
2-[(5,6-dimethyl-2-propyl-4-thieno[2,3-d]pyrimidinyl)thio]-1-(2-methyl-2,3-dihydroindol-1-yl)ethanone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
2-[(3-ethyl-6-methyl-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)thio]-N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
5-[2-furanyl(4-morpholinyl)methyl]-2-methyl-6-thiazolo[3,2-b][1,2,4]triazolol	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-[5-(ethylthio)-1,3,4-thiadiazol-2-yl]-2-[[3-(2-methoxyphenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]thio]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3,8-dimethyl-4-oxo-7,8,9,10-tetrahydro-6H-thieno[1,2]pyrimido[4,5-a]azepine-2-carboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3,7-dimethyl-2-(methylthio)-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-[2-[(2-ethoxy-2-oxoethyl)thio]-4-oxo-3-thieno[3,2-d]pyrimidinyl]-1-piperidinecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-(1,3-benzodioxol-5-yl)-2-[[6-methyl-4-oxo-3-(phenylmethyl)-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]thio]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2,5-dimethyl-4-(4-methyl-1-piperidinyl)-6-thieno[2,3-d]pyrimidinecarboxylic acid	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
N-[[4-(dimethylamino)phenyl]methyl]-3-ethyl-N-(2-furanylmethyl)-5-methyl-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-(1,3-benzodioxol-5-yl)-3-ethyl-5-methyl-4-oxo-6-thieno[2,3-d]pyrimidinecarboxamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-[3-(2,4-dioxo-1H-thieno[3,2-d]pyrimidin-3-yl)-1-oxopropyl]-1-piperazinecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[[3-(2-methoxyethyl)-6-methyl-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]thio]-N-(2-oxolanylmethyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
LSM-16990	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-[1-oxo-6-(4-oxo-2-sulfanylidene-1H-thieno[3,2-d]pyrimidin-3-yl)hexyl]-1-piperazinecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[(4-amino-7-tert-butyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl)thio]acetic acid	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-(4-chlorophenyl)-5-methyl-4-oxo-2,3-dihydro-1H-thieno[3,4-d]pyrimidine-7-carboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[(3-ethyl-7-methyl-4-oxo-6,8-dihydro-5H-pyrido[2,3]thieno[2,4-b]pyrimidin-2-yl)thio]-N-(2-phenylethyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-[[2-[(1,1-dioxo-3-thiolanyl)amino]-2-oxoethyl]thio]-2,5-dimethyl-6-thieno[2,3-d]pyrimidinecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
5-[2-furanyl(4-morpholinyl)methyl]-6-thiazolo[3,2-b][1,2,4]triazolol	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-(5-chloro-2-methoxyphenyl)-2-[[3-(2-methoxyethyl)-6-methyl-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]thio]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
LSM-22688	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-furanyl-[4-[(6-hydroxy-2-methyl-5-thiazolo[3,2-b][1,2,4]triazolyl)-thiophen-2-ylmethyl]-1-piperazinyl]methanone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-(5-methyl-3-isoxazolyl)-2-[(6-methyl-4-oxo-3-phenyl-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl)thio]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3-(2,4-dioxo-1H-thieno[3,2-d]pyrimidin-3-yl)-N-(3-fluoro-4-methylphenyl)propanamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-(3-methoxyphenyl)-3,5,6,7,8,9-hexahydrocyclohepta[2,3]thieno[2,4-b]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3-[(2,5,6-trimethyl-4-thieno[2,3-d]pyrimidinyl)thio]-2-oxolanone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
2-[[3-[2-(diethylamino)ethyl]-4-oxo-[1]benzothiolo[3,2-d]pyrimidin-2-yl]thio]-N-(phenylmethyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2,5-dimethyl-4-[[2-oxo-2-(4-phenylbutan-2-ylamino)ethyl]thio]-6-thieno[2,3-d]pyrimidinecarboxylic acid ethyl ester	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
cornexistin	[no description available]	low	cyclic dicarboxylic anhydride; organic heterobicyclic compound; secondary alpha-hydroxy ketone	herbicide; metabolite
geldanamycin	[no description available]	low	1,4-benzoquinones; ansamycin; carbamate ester; organic heterobicyclic compound	antimicrobial agent; antineoplastic agent; antiviral agent; cysteine protease inhibitor; Hsp90 inhibitor
trandolaprilat	[no description available]	low	dicarboxylic acid; dipeptide; organic heterobicyclic compound; secondary amino compound; tertiary carboxamide	antihypertensive agent; drug metabolite; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; human xenobiotic metabolite
trandolapril	[no description available]	low	dicarboxylic acid monoester; dipeptide; ethyl ester; organic heterobicyclic compound; secondary amino compound; tertiary carboxamide	antihypertensive agent; EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor; prodrug
6-[(4-fluorophenyl)methyl]-5,7-dimethyl-2H-pyrrolo[3,4-d]pyridazin-1-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound
manumycin	[no description available]	low	enamide; epoxide; organic heterobicyclic compound; polyketide; secondary carboxamide; tertiary alcohol	antiatherosclerotic agent; antimicrobial agent; antineoplastic agent; apoptosis inducer; bacterial metabolite; EC 1.8.1.9 (thioredoxin reductase) inhibitor; EC 2.5.1.58 (protein farnesyltransferase) inhibitor; marine metabolite
aurachin c	[no description available]	low	C-type aurachin; hydroxylamines; organic heterobicyclic compound; quinolone	antibacterial agent; bacterial metabolite; EC 1.8.5.4 (sulfide:quinone reductase) inhibitor
asukamycin	[no description available]	low	enamide; epoxide; organic heterobicyclic compound; polyketide; secondary carboxamide; tertiary alcohol	antibacterial agent; antifungal agent; antimicrobial agent; antineoplastic agent; bacterial metabolite
2-[(3,6-dimethyl-4-oxo-2-thieno[2,3-d]pyrimidinyl)thio]-N-(4-methylphenyl)acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
tanespimycin	[no description available]	low	1,4-benzoquinones; ansamycin; carbamate ester; organic heterobicyclic compound; secondary amino compound	antineoplastic agent; apoptosis inducer; Hsp90 inhibitor
ly 404039	[no description available]	low	bridged compound; dicarboxylic acid; non-proteinogenic amino acid derivative; organic heterobicyclic compound; sulfone	antipsychotic agent; anxiolytic drug; dopamine agonist; metabotropic glutamate receptor agonist
PI3-Kinase alpha Inhibitor 2	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
ly 379268	[no description available]	low	amino dicarboxylic acid; bridged compound; organic heterobicyclic compound	antipsychotic agent; anxiolytic drug; metabotropic glutamate receptor agonist; neuroprotective agent
marizomib	[no description available]	low	beta-lactone; gamma-lactam; organic heterobicyclic compound; organochlorine compound; salinosporamide	antineoplastic agent; proteasome inhibitor
ceratamine a	[no description available]	low	alkaloid; aromatic ether; cyclic ketone; organic heterobicyclic compound; organobromine compound; secondary amino compound; tertiary amine	antimitotic; metabolite
complestatin	[no description available]	low	cyclic ether; heterodetic cyclic peptide; indoles; organic heterobicyclic compound; organochlorine compound; peptide antibiotic; polyphenol	anti-HIV-1 agent; antimicrobial agent; HIV-1 integrase inhibitor; metabolite
N-(2-furanylmethyl)-2-[[4-oxo-3-[3-(1-pyrrolidinyl)propyl]-[1]benzothiolo[3,2-d]pyrimidin-2-yl]thio]acetamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-[3-[butyl(ethyl)amino]propyl]-1-(9-fluoro-[1]benzothiolo[3,2-d]pyrimidin-4-yl)-4-piperidinecarboxamide	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[(5,6-dimethyl-4-thieno[2,3-d]pyrimidinyl)amino]-1-(4-nitrophenyl)ethanol	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound; thienopyrimidine
sm 164	[no description available]	low	benzenes; organic heterobicyclic compound; secondary carboxamide; triazoles	antineoplastic agent; apoptosis inducer; radiosensitizing agent
spiruchostatin b	[no description available]	low	macrocyclic lactone; organic disulfide; organic heterobicyclic compound; spiruchostatin	antineoplastic agent; bacterial metabolite; EC 3.5.1.98 (histone deacetylase) inhibitor
pf 3758309	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2,4-dimethyl-6-phenyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
6-[(2-fluorophenyl)methyl]-2-(1-hydroxyethyl)-4-methyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
6-[(3-methoxyphenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
6-[(3-aminophenyl)methyl]-4-methyl-2-methylsulfinyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-bromo-6-[(2-chloro-6-fluorophenyl)methyl]-4-methyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-bromo-6-[(2,4-difluorophenyl)methyl]-4-methyl-5-thieno[3,4]pyrrolo[1,3-d]pyridazinone	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
tropodithietic acid	[no description available]	low	cyclic ketone; monocarboxylic acid; organic disulfide; organic heterobicyclic compound; organosulfur heterocyclic compound	antibacterial agent; bacterial metabolite; marine metabolite; signalling molecule; toxin
mycalamide b	[no description available]	low	organic heterobicyclic compound; oxacycle
streptolydigin	[no description available]	low	bridged compound; cyclic ketal; enol; monocarboxylic acid amide; N-glycosyl compound; organic heterobicyclic compound; pyrrolidinone; spiro-epoxide	antimicrobial agent; bacterial metabolite; EC 2.7.7.6 (RNA polymerase) inhibitor
allopurinol	[no description available]	low	nucleobase analogue; organic heterobicyclic compound	antimetabolite; EC 1.17.3.2 (xanthine oxidase) inhibitor; gout suppressant; radical scavenger
1,4-Dihydrothieno[3,2-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
7-Methyl-3,4-dihydrothieno[3,2-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
3,n(4)-ethanocytosine	[no description available]	low	organic heterobicyclic compound	mutagen
7,9-dimethyl-2-(phenylmethylthio)-1H-pyrido[2,3]thieno[2,4-b]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-[[(6-methyl-5-oxo-2H-1,2,4-triazin-3-yl)thio]methyl]-5,6,7,8-tetrahydro-3H-[1]benzothiolo[2,3-d]pyrimidin-4-one	[no description available]	low	organic heterobicyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
ellipticine	[no description available]	low	indole alkaloid; organic heterotetracyclic compound; organonitrogen heterocyclic compound; polycyclic heteroarene	antineoplastic agent; plant metabolite
hexetidine	[no description available]	low	organic heteromonocyclic compound; organonitrogen heterocyclic compound
ro 15-4513	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound
tebuthiuron	[no description available]	low	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
skimmianine	[no description available]	low	alkaloid antibiotic; organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
benz(a)acridine	[no description available]	low	organonitrogen heterocyclic compound; polycyclic heteroarene
benz(c)acridine	[no description available]	low	organonitrogen heterocyclic compound; polycyclic heteroarene
kokusaginine	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
quinacridone	[no description available]	low	organic heterotetracyclic compound; organonitrogen heterocyclic compound
nicergoline	[no description available]	low	organic heterotetracyclic compound; organonitrogen heterocyclic compound
acetosulfame	[no description available]	low	organic heteromonocyclic compound; organonitrogen heterocyclic compound; oxacycle; sulfamate ester	environmental contaminant; sweetening agent; xenobiotic
web 2086	[no description available]	low	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
dictamnine	[no description available]	low	alkaloid antibiotic; organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
flindersiamine	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
flindersine	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
maculine	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
Evoxine	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
tryptanthrine	[no description available]	low	alkaloid antibiotic; organic heterotetracyclic compound; organonitrogen heterocyclic compound
cryptolepine	[no description available]	low	indole alkaloid; organic heterotetracyclic compound; organonitrogen heterocyclic compound	anti-inflammatory agent; antimalarial; antineoplastic agent; cysteine protease inhibitor; plant metabolite
9-hydroxyellipticine	[no description available]	low	organic heterotetracyclic compound; organonitrogen heterocyclic compound	antineoplastic agent
tylophorine	[no description available]	low	organic heteropentacyclic compound; organonitrogen heterocyclic compound
gamma-fagarine	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
propizepine	[no description available]	low	organonitrogen heterocyclic compound
dechloroethylifosfamide	[no description available]	low	organonitrogen heterocyclic compound; organophosphorus compound
ro 19-4603	[no description available]	low	organonitrogen heterocyclic compound; organosulfur heterocyclic compound; tert-butyl ester
11-deoxytetrodotoxin	[no description available]	low	organic heteromonocyclic compound; organonitrogen heterocyclic compound
diflomotecan	[no description available]	low	epsilon-lactone; organic heteropentacyclic compound; organofluorine compound; organonitrogen heterocyclic compound; tertiary alcohol	antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor
pd 146176	[no description available]	low	organic heterotetracyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound	antiatherogenic agent; EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor; ferroptosis inhibitor
Dubinidine	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
1-[4-amino-3-[2-(1-pyrrolidinyl)ethylthio]-5-thieno[2,3-c]isothiazolyl]ethanone	[no description available]	low	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
2-methyl-2,3,4,5-tetrahydro-1,5-benzoxazepin-4-one	[no description available]	low	organonitrogen heterocyclic compound; oxacycle
folicanthine	[no description available]	low	aminal; calycanthaceous alkaloid; organonitrogen heterocyclic compound
haplamine	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
(2R)-1-[(4,8-dimethoxy-7-furo[2,3-b]quinolinyl)oxy]-3-methylbutane-2,3-diol	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
9-ethyl-1,2,4,5-tetrazaspiro[5.5]undecane-3-thione	[no description available]	low	organonitrogen heterocyclic compound
5-amino-3-(2-methylphenyl)-4-oxo-1-thieno[3,4-d]pyridazinecarboxylic acid ethyl ester	[no description available]	low	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-[(2,6-dichlorophenyl)thio]-5-methoxy-2-(2-pyridinyl)pyrimidine	[no description available]	low	organonitrogen heterocyclic compound
4-[(4-chloro-1-naphthalenyl)oxy]-5-methoxy-2-(2-pyridinyl)pyrimidine	[no description available]	low	organonitrogen heterocyclic compound
4-(2,6-dimethylphenoxy)-5-methoxy-2-(2-pyridinyl)pyrimidine	[no description available]	low	organonitrogen heterocyclic compound
N-[(4-methylphenyl)methyl]-2-(2-pyridinyl)-4-(trifluoromethyl)-5-pyrimidinecarboxamide	[no description available]	low	organonitrogen heterocyclic compound
4-(2-chlorophenoxy)-2-(2-pyridinyl)-6-(trifluoromethyl)pyrimidine	[no description available]	low	organonitrogen heterocyclic compound
6-methyl-12-indolo[1,2-c]quinazolinamine	[no description available]	low	organic heterotetracyclic compound; organonitrogen heterocyclic compound
4-(4-methyl-1-piperidinyl)-5-phenyl-2-(3-pyridinyl)thieno[2,3-d]pyrimidine	[no description available]	low	organonitrogen heterocyclic compound; thienopyrimidine
N-[3-(4-morpholinyl)propyl]-3-(3-pyridinyl)-7,8-dihydro-6H-cyclopenta[4,5]thieno[1,2-c]pyrimidin-1-amine	[no description available]	low	organonitrogen heterocyclic compound
4-[5-chloro-6-methyl-2-(2-pyridinyl)-4-pyrimidinyl]morpholine	[no description available]	low	organonitrogen heterocyclic compound
8,10-dimethyl-4-(2-methylphenyl)-1,3-dihydropyrido[2,3]thieno[2,4-d][1,4]diazepine-2,5-dione	[no description available]	low	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
quinagolide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound
4-[oxo-(4-oxo-5H-thieno[3,2-c]quinolin-2-yl)methyl]-1-piperazinecarboxylic acid ethyl ester	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-(7-methoxy-2-furo[2,3-b]quinolinyl)methanone	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
1-[(6-methoxy-2-furo[2,3-b]quinolinyl)-oxomethyl]-4-piperidinecarboxylic acid ethyl ester	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
N-[2-(dipropylamino)ethyl]-4-methyl-2-furo[3,2-c]quinolinecarboxamide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
6-methoxy-N-(thiophen-2-ylmethyl)-2-furo[2,3-b]quinolinecarboxamide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
4-(2-chlorophenoxy)-5-methoxy-2-(2-pyridinyl)pyrimidine	[no description available]	low	organonitrogen heterocyclic compound
7-methoxy-N-(3-pyridinylmethyl)-2-furo[2,3-b]quinolinecarboxamide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
N-[(4-ethoxy-3-methoxyphenyl)methyl]-N-methyl-2-(3-pyridinyl)-4-quinazolinamine	[no description available]	low	organonitrogen heterocyclic compound
acetic acid [1-[(4,8-dimethoxy-7-furo[2,3-b]quinolinyl)oxy]-3-hydroxy-3-methylbutan-2-yl] ester	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
heliparvifoline	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
5-ethyl-4-oxo-N-(thiophen-2-ylmethyl)-2-thieno[3,2-c]quinolinecarboxamide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
calycanthine	[no description available]	low	aminal; calycanthaceous alkaloid; organonitrogen heterocyclic compound
1-azakenpaullone	[no description available]	low	lactam; organic heterotetracyclic compound; organobromine compound; organonitrogen heterocyclic compound	EC 2.7.11.26 (tau-protein kinase) inhibitor; Wnt signalling activator
4-methyl-N-[(4-methylphenyl)methyl]-2-furo[3,2-c]quinolinecarboxamide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
lergotrile	[no description available]	low	organic heterotetracyclic compound; organonitrogen heterocyclic compound
3-(2-pyridinyl)-6-(2-pyridinylmethylthio)pyridazine	[no description available]	low	organonitrogen heterocyclic compound
N-cyclohexyl-2-[[6-(2-pyridinyl)-3-pyridazinyl]thio]acetamide	[no description available]	low	organonitrogen heterocyclic compound
N-cyclopentyl-2-[[6-(2-pyridinyl)-3-pyridazinyl]thio]acetamide	[no description available]	low	organonitrogen heterocyclic compound
5-(1-phenyl-5-tetrazolyl)-2-pyridin-4-yl-4-thiophen-2-ylpyrimidine	[no description available]	low	organonitrogen heterocyclic compound
5-amino-4-oxo-3-phenyl-1-thieno[3,4-d]pyridazinecarboxylic acid	[no description available]	low	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
muromonab-cd3	[no description available]	low	alkaloid; macrocycle; organic heteropentacyclic compound; organonitrogen heterocyclic compound; oxacycle; tertiary amino compound	antineoplastic agent; EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor; IP3 receptor antagonist; marine metabolite
6h-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-n-(4-hydroxyphenyl)-2,3,9-trimethyl-, (6s)-	[no description available]	low	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
homocamptothecin	[no description available]	low	epsilon-lactone; organic heteropentacyclic compound; organonitrogen heterocyclic compound; tertiary alcohol	antineoplastic agent; EC 5.99.1.2 (DNA topoisomerase) inhibitor
jnj16259685	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
imidazolone	[no description available]	low	organonitrogen heterocyclic compound
3-[(6aR,9R,10aR)-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-yl]-1,1-diethylurea	[no description available]	low	organic heterotetracyclic compound; organonitrogen heterocyclic compound
4-chloro-N-(3,4-dimethoxyphenyl)-2-thieno[3,2-c]quinolinecarboxamide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
4-chloro-N-[3-(3-methyl-1-piperidinyl)propyl]-2-thieno[3,2-c]quinolinecarboxamide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
8-methyl-4-oxo-N-[3-(4-propyl-1-piperazinyl)propyl]-5H-thieno[3,2-c]quinoline-2-carboxamide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N,8-dimethyl-N-(3-methylphenyl)-4-oxo-5H-thieno[3,2-c]quinoline-2-carboxamide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-[2-(dipropylamino)ethyl]-5-ethyl-4-oxo-2-thieno[3,2-c]quinolinecarboxamide	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; organosulfur heterocyclic compound
N-[5-[6-(3-chloroanilino)-4-pyrimidinyl]-2-pyridinyl]-N',N'-dimethylpropane-1,3-diamine	[no description available]	low	organonitrogen heterocyclic compound
LSM-6732	[no description available]	low	organonitrogen heterocyclic compound; organosulfur heterocyclic compound; tert-butyl ester
4-hydroxy-6-propan-2-ylpyrano[3,2-c]quinoline-2,5-dione	[no description available]	low	organic heterotricyclic compound; organonitrogen heterocyclic compound; oxacycle
3-[[2-(2-pyridinyl)-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)-4-pyrimidinyl]amino]propanoic acid	[no description available]	low	organonitrogen heterocyclic compound
gsk-j4	[no description available]	low	organonitrogen heterocyclic compound
2-pyridin-4-yl-1H-quinazolin-4-one	[no description available]	low	organonitrogen heterocyclic compound
bentazepam	[no description available]	low	organonitrogen heterocyclic compound; organosulfur heterocyclic compound
scytonemin	[no description available]	low	enone; organic heterotricyclic compound; organonitrogen heterocyclic compound; polyphenol; ring assembly	bacterial metabolite; biological pigment; ultraviolet filter
ketotifen	[no description available]	low	cyclic ketone; olefinic compound; organic heterotricyclic compound; organosulfur heterocyclic compound; piperidines; tertiary amino compound	anti-asthmatic drug; H1-receptor antagonist
thianthrene	[no description available]	low	mancude organic heterotricyclic parent; organosulfur heterocyclic compound; thianthrenes
benzo(b)naphtho(2,1-d)thiophene	[no description available]	low	organic heterotricyclic compound; organosulfur heterocyclic compound
ethylene sulfide	[no description available]	low	organosulfur heterocyclic compound; saturated organic heteromonocyclic parent
carboxin	[no description available]	low	anilide fungicide; anilide; enamide; organosulfur heterocyclic compound; oxacycle; secondary carboxamide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
oxycarboxin	[no description available]	low	anilide fungicide; anilide; organosulfur heterocyclic compound; oxacycle; sulfone	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
thiarubrine a	[no description available]	low	organosulfur heterocyclic compound
tetrathiafulvalene	[no description available]	low	fulvalenes; organosulfur heterocyclic compound
1-cyano-3,4-epithiobutane	[no description available]	low	organosulfur heterocyclic compound; saturated organic heteromonocyclic parent
2,6-diamino-4-(1-phenylethyl)-4H-thiopyran-3,5-dicarbonitrile	[no description available]	low	nitrile; organosulfur heterocyclic compound
6-amino-3-(methoxymethyl)-5-spiro[2H-pyrano[2,3-c]pyrazole-4,4'-thiane]carbonitrile	[no description available]	low	nitrile; organic sulfide; organosulfur heterocyclic compound; oxaspiro compound
2-[[2-furanyl(oxo)methyl]amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid ethyl ester	[no description available]	low	organosulfur heterocyclic compound
N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-3-methylbenzamide	[no description available]	low	organosulfur heterocyclic compound
N-(1,2,4-triazol-4-yl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carboxamide	[no description available]	low	organosulfur heterocyclic compound
2-benzamido-4,5-dihydrobenzo[g][1]benzothiole-3-carboxamide	[no description available]	low	organic heterotricyclic compound; organosulfur heterocyclic compound
LSM-33589	[no description available]	low	organic heterotricyclic compound; organosulfur heterocyclic compound
Thiophene-2	[no description available]	low	organosulfur heterocyclic compound
4-[(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)amino]-4-oxobutanoic acid	[no description available]	low	organosulfur heterocyclic compound
2-[[(4-fluoro-2-nitroanilino)-sulfanylidenemethyl]amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylic acid methyl ester	[no description available]	low	organosulfur heterocyclic compound
N-(2-furanylmethyl)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide	[no description available]	low	organosulfur heterocyclic compound
2-[[[4-[bis(2-methoxyethyl)sulfamoyl]phenyl]-oxomethyl]amino]-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide	[no description available]	low	organosulfur heterocyclic compound
N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)-2-oxolanecarboxamide	[no description available]	low	organosulfur heterocyclic compound
1-cyclohexyl-3-(1,1-dioxo-2,5-dihydrothiophen-3-yl)-1-methylthiourea	[no description available]	low	organosulfur heterocyclic compound
norketotifen	[no description available]	low	organosulfur heterocyclic compound

Condition	Indicated	Relationship Strength	Studies	Trials
Inflammation	0	low	1	0
Innate Inflammatory Response	0	low	1	0

2-[2-(dimethylamino)ethylthio]-6,6-dimethyl-5,8-dihydropyrano[4,5]thieno[1,2-c]pyrimidin-4-amine

Cross-References

Synonyms (11)

Drug Classes (3)

Protein Targets (13)

Potency Measurements

Biological Processes (17)

Molecular Functions (8)

Ceullar Components (5)

Bioassays (13)

Research

Studies (5)

Study Types

2-[2-(dimethylamino)ethylthio]-6,6-dimethyl-5,8-dihydropyrano[4,5]thieno[1,2-c]pyrimidin-4-amine

Cross-References

Synonyms (11)

Drug Classes (3)

Protein Targets (13)

Potency Measurements

Biological Processes (17)

Molecular Functions (8)

Ceullar Components (5)

Bioassays (13)

Research

Studies (5)

Study Types

Related Drugs (267)

Related Conditions (2)